Search for dissertations about: "pore-forming toxin"

Showing result 1 - 5 of 15 swedish dissertations containing the words pore-forming toxin.

  2. 1. Studies of pore-forming bacterial protein toxins in Escherichia coli

    Author : Constance Enow; Bernt Eric Uhlin; Sun Nyunt Wai; Mikael Rehn; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; molekylärbiologi; Molecular Biology;

    Abstract : Escherichia coli, a Gram-negative bacterium, which can be classified into three groups: the commensal, intestinal pathogenic (IPEC) and extra-intestinal pathogenic (ExPEC) E. coli. The cytolysin A (ClyA) protein, a 34-kDa pore-forming toxin, encoded by a gene found in both non-pathogenic and pathogenic E. READ MORE

  4. 2. Roles of membrane vesicles in bacterial pathogenesis

    Author : Svitlana Vdovikova; Sun Nyunt Wai; Richard Lundmark; Ann-Beth Jonsson; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Membrane vesicles; autophagy; pore-forming toxin; pore formation; Listeria monocytogenes; Vibrio cholerae; virulence factor; PrtV protease; listeriolysin O; V. cholerae cytolysin; mikrobiologi; Microbiology; molekylärbiologi; Molecular Biology;

    Abstract : The production of membranous vesicles is observed to occur among organisms from all domains of the tree of life spanning prokaryotes (bacteria, archaea) and eukaryotes (plants, animals and fungi). Bacterial release of membrane-derived vesicles (MVs) has been studied most extensively in cases of Gram-negative species and implicating their outer membrane in formation of extracellular MVs. READ MORE

  5. 3. Pathogen entry mechanisms and endocytic responses to plasma membrane damage

    Author : Lars Nygård Skalman; Richard Lundmark; Kristian Riesbeck; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Endocytosis; plasma membrane; pathogens; virus; bacterial membrane vesicles; Helicobacter pylori; adenovirus 37; listeriolysin O; pore-forming toxins; membrane repair;

    Abstract : Endocytosis is a fundamental cellular process by which cells transport material from the outside to the inside of the cell through the formation of membrane invaginations that bud off from the plasma membrane. This process is important for nutrient uptake, regulating cell surface receptors and the overall plasma membrane composition. READ MORE

  6. 4. Toxin production in clostridium difficile

    Author : Sture Karlsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Clostridium difficile is a is a Gram potential human pathogen. It causing symptoms ranging from mild C. difficile associated diarrhea (CDAD) to severe inflammation of the colon including pseudomembranous colitis and fulminant colitis. Over 300 000 and about 10 000 CDAD episodes are diagnosed annually in the USA and Sweden, respectively. READ MORE

  7. 5. Novel signaling pathways : induced by bacterial toxins in eukaryotic cells

    Author : Camilla Oxhamre; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Inflammation is the process by which the host counteracts microbes that are constantly exposing the human body. These microbes rarely cause disease, due to the effective defense mechanisms of the host immune system. Although inflammation is essential for preventing infections, it can also damage the host. READ MORE