Search for dissertations about: "in situ generation"

Showing result 1 - 5 of 138 swedish dissertations containing the words in situ generation.

  2. 1. In situ Sequencing : Methods for spatially-resolved transcriptome analysis

    Author : Marco Mignardi; Mats Nilsson; Xiaoliang Sunney Xie; Stockholms universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Padlock probes; rolling circle amplification; in situ sequencing; spatially-resolved transcriptomics; molecular diagnostics; Biochemistry; biokemi;

    Abstract : It is well known that cells in tissues display a large heterogeneity in gene expression due to differences in cell lineage origin and variation in the local environment at different sites in the tissue, a heterogeneity that is difficult to study by analyzing bulk RNA extracts from tissue. Recently, genome-wide transcriptome analysis technologies have enabled the analysis of this variation with single-cell resolution. READ MORE

  4. 2. On the deformation behavior and cracking of ductile iron; effect of microstructure

    Author : Keivan Amiri Kasvayee; Anders E.W. Jarfors; Jens Bergström; Jönköping University; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Spherical graphite iron; component casting; high silicon ductile iron; digital image correlation DIC ; in-situ tensile testing; in-situ cyclic testing; DIC pattern generation; pit etching; micro-scale deformation; micro-crack; finite element analysis FEA ; focused ion beam FIB milling; segjärn; komponentgjutning; högkisellegerat segjärn; digital image correlation DIC ; insitu dragprovning; in-situ cyklisk provning; DIC-mönstergenerering; grop-etsning; mikroskalig deformation; mikrosprickor; finite element analys FEA ; fokuserad jonstråle FIB avverkning;

    Abstract : This thesis focuses on the effect of microstructural variation on the mechanical properties and deformation behavior of ductile iron. To research and determine these effects, two grades of ductile iron, (i) GJS-500-7 and (ii) high silicon GJS-500-14, were cast in a geometry containing several plates with different section thicknesses in order to produce microstructural variation. READ MORE

  5. 3. Magma generation and formation of continental crust in the Izu arc

    Author : Haochen Duan; Abigail Barker; Jaroslaw Majka; Stefan Wastegård; Kate Saunders; Susanne M. Straub; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Oceanic arc; Izu rear-arc; Melt inlcusions; Oxygen isotopes; Boron isotopes; Continental crust; Mantle hererogeneity; In-situ microanalysis; IMS-1280; Geovetenskap med inriktning mot mineralogi; petrologi och tektonik; Earth Science with specialization in Mineral Chemistry; Petrology and Tectonics;

    Abstract : The Izu oceanic arc is produced by the subduction of the Pacific Sea Plate beneath the Philippine Sea Plate. The proto-Izu oceanic arc was initially formed at ca. 50 Ma, then it was separated into the Kyushu-Palau and Izu arc by the extension of the Shikoku basin from ca. 25 Ma. READ MORE

  6. 4. Domain engineering in KTiOPO4

    Author : Carlota Canalias; Fredrik Laurell; Benoît Boulanger; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; quasi-phase matching; KTiOPO4; ferroelectric domains; atomic force microscopy; periodic electric field poling; polarization switching; second harmonic generation; Optical physics; Optisk fysik;

    Abstract : Ferroelectric crystals are commonly used in nonlinear optics for frequency conversion of laser radiation. The quasi-phase matching (QPM) approach uses a periodically modulated nonlinearity that can be achieved by periodically inverting domains in ferroelectric crystals and allows versatile and efficient frequency conversion in the whole transparency region of the material. READ MORE

  7. 5. Generation of induced neurons via direct conversion in vivo and in vitro

    Author : Olof Torper; Neurobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cellular reprogramming; cell replacement therapies; induced dopaminergic neurons; in vivo reprogramming; Lentiviral vectors; AAV vectors;

    Abstract : Cellular reprogramming is when one cell is changed into another. This involves structural modifications on the DNA of a cell resulting in a transcriptional change. This occurs naturally during development when early pluripotent cells gradually differentiate into more specialized cells that finally result in a complete organism. READ MORE