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Found 3 swedish dissertations matching the above criteria.

  1. 1. Molecular genetic aspects of renal cell carcinoma development

    Author : Andrei Alimov; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Kidney tumor; RCC; LOH; CGH; SKY; PTEN; chromosome 3p; chromosome 10q; chromosome 14q;

    Abstract : Renal cell carcinoma (RCC) is the most common tumor of the renal parenchyma. The aim of this study was to further characterize known as well as new genetic abnormalities in a clinical material of RCC, as well as in established cell lines to gain more information about etiological and progression factors. READ MORE

  2. 2. Molecular cytogenetic investigations of chromosomal abnormalities in prostate and urinary bladder cancers

    Author : Yi Pan; Karolinska Institutet; Karolinska Institutet; []
    Keywords : prostate cancer; bladder cancer; FISH; SKY;

    Abstract : Tumorigenesis is suggested to be caused by base pair mutations and chromosomal abnormalities leading to inactivation of tumor suppressor genes an activation of oncogenes. However, still it is not clear for the vast majority of these changes how they contribute to the tumorigenesis of the prostate and bladder cancers. READ MORE

  3. 3. Molecular genetics of kidney cancer : chromosomal regions of importance in the development of renal cell carcinoma

    Author : Rikard Erlandsson; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Carcinoma; renal cell Chromosomes; human; pair 3 Chromosome deletion Genes; suppressor; tumor Sequence analysis; DNA. Renal cell carcinoma RCC is a malignancy of the human kidney; occurring most commonlyduring the seventh and eighth decades of;

    Abstract : Renal cell carcinoma (RCC) is a malignancy of the human kidney, occurring most commonly during the seventh and eighth decades of life. The incidence is high in the Nordic countries and the five year survival is 40-50%. Smoking is a risk factor inferring a minor increase in risk. The best established risk factor is obesity. READ MORE