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Showing result 1 - 5 of 79 swedish dissertations matching the above criteria.
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1. Proteomic strategies for analysis of cerebrospinal fluid in neurodegenerative disorders
Abstract : ABSTRACT There is a great need for biomarkers to diagnose neurodegenerative disorders, such as the cognitive disorders Alzheimer?s disease (AD) and frontotemporal dementia (FTD). Cerebrospinal fluid (CSF) is in contact with the extracellular fluid of the brain and is consequently a valuable medium for identifying biomarkers for neurological disorders. READ MORE
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2. Idiopathic Normal Pressure Hydrocephalus : Cerebrospinal Fluid Tap Test and Magnetic Resonance Imaging as Preoperative Prognostic Investigations
Abstract : Idiopathic normal pressure hydrocephalus (iNPH) is a condition with dilated cerebral ventricles but intracranial pressure within normal limits. The symptoms of gait impairment, cognitive decline and urinary incontinence develop gradually. Treatment with shunt insertion results in improvement in eight out of ten patients. READ MORE
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3. Development of proteomic methods for studying cerebrospinal fluid proteins involved in Alzheimer´s disease
Abstract : Alzheimer's disease (AD) is the most common cause of dementia in western countries. The main neuropathological findings in the AD brain are senile plaques, neurofibrillary tangles and degeneration of neurons and synapses. READ MORE
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4. Candidate biomarkers for synaptic pathology: neurogranin, neuroligins and neurexins in neurodegenerative disorders
Abstract : Synapses are small units through which neurons communicate in the brain. They represent the site of memory formation and cognitive abilities and are thus primarily affected by neurodegenerative diseases such as Alzheimer’s disease (AD), the leading cause of dementia in the elderly population. READ MORE
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5. Biomarkers in Parkinson's disease and related disorders. Diagnostic value of biochemical markers and their relation to disease progression
Abstract : .... READ MORE