Search for dissertations about: "cortisol excess"

Showing result 1 - 5 of 12 swedish dissertations containing the words cortisol excess.

  2. 1. Clinical challenges in Cushing's syndrome

    Author : Eleni Papakokkinou; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cushing’s syndrome; Cushing’s disease; cortisol excess; Nelson’s syndrome; morbidity; remission; mental fatigue; cognitive function; adrenal venous sampling;

    Abstract : Cushing’s syndrome (CS) is caused by prolonged exposure to cortisol excess. CS is associated with cardiovascular diseases, infections, and fractures, as well as with cognitive impairment and affective disorders. READ MORE

  4. 2. Glucocorticoid administration : studies on weight regulation and metabolic implications

    Author : Joanna Uddén; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Glucocorticoids; leptin; obesity; adipose tissue; PAI-1; UCP-2; cortisol; the metabolic syndrome; 11 beta-HSD; eating behaviour; weight gain.;

    Abstract : Long-term treatment with glucocorticoids induces weight gain and increased risk to develop obesity-related metabolic complications like insulin resistance, type 2 diabetes and cardiovascular disease. Glucocorticoids have been suggested to play a role in development of visceral fat accumulation. READ MORE

  5. 3. Adrenocortical tumors : Diagnosis, growth regulation and treatment

    Author : Carin Backlin; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Kirurgi; Surgery; Kirurgi; Surgery; kirurgi;

    Abstract : Monoclonal antibodies generated by immunization with human adrenocortical cells reacted with the normal adrenal cortex, adrenocortical adenomas and carcinomas, but failed to stain a variety of normal tissues, renal cell carcinoma, and pheocromocytomas. The antibodies can be used to improve histological diagnosis and characterization of human adrenal lesions, and possibly for scintigraphic detection. READ MORE

  6. 4. Congenital adrenal hyperplasia, CYP21 deficiency, screening and clinical aspects

    Author : Anna Nordenström; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Congenital adrenal hyperplasia; 21 -hydroxylase deficiency; CYP21; neonatal screening; 17-OHP; sex-typed behavior; toy play.;

    Abstract : Congenital adrenal hyperplasia (CAH) is a group of recessively inherited disorders. More than 90% of all cases of CAB are caused by 21-hydroxylase deficiency. This enzyme deficiency results in reduced ability to synthesize cortisol and aldosterone and at the same time increased secretion of androgens. READ MORE

  7. 5. Insights into the transcriptomic profiling of adrenocortical tumors

    Author : David Velázquez-Fernández; Karolinska Institutet; Karolinska Institutet; []
    Keywords : Adrenocortical tumours;

    Abstract : An adrenocortical tumour (ACT) can be detected in up to 5% of the population older than 50 years of age. The frequency increases with age. More ACTs are being detected in parallel with the increased use of high-resolution imaging. READ MORE