Search for dissertations about: "hrg"

Showing result 11 - 15 of 15 swedish dissertations containing the word hrg.

  2. 11. Investigations of Proneural Glioblastoma to Identify Novel Therapeutic Targets

    Author : Maria Boije; Lene Uhrbom; Bengt Westermark; Rolf Bjerkvig; Uppsala universitet; []
    Keywords : Glioma; proneural subtype; hallmarks; glioma initiating cells; S-SOX5; angiogenesis; stromal cells; Tumour biology; Tumörbiologi; Experimentell patologi; Experimental Pathology;

    Abstract : Malignant glioma is a highly lethal and destructive disease with no proper cure. We have investigated some of the hallmarks of cancer in connection to glioma and found ways to disrupt these and prevent tumor growth. The work is done within the context of a glioma subtype distinguished by activation of PDGF signaling termed the proneural subtype. READ MORE

  4. 12. Towards semantic language processing

    Author : Anna Jonsson; Johanna Björklund; Marco Kuhlmann; Umeå universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Weighted tree automata; abstract meaning representation; contextual hyperedge replacement grammar; hyperedge replacement grammar; semantic modelling; the N best problem; Computer Science; datalogi; datorlingvistik; computational linguistics;

    Abstract : The overall goal of the field of natural language processing is to facilitate the communication between humans and computers, and to help humans with natural language problems such as translation. In this thesis, we focus on semantic language processing. READ MORE

  5. 13. Cellular Origin and Development of Glioma

    Author : Nanna Lindberg; Lene Uhrbom; Bengt Westermark; Kristian Pietras; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioma; brain tumor; PDGF; RCAS TV-A; cell of origin; glial cell; oligodendrocyte progenitor cell; DNA repair; homology-directed repair; RAD51; angiogenesis; histidine-rich glycoprotein; Morphology; cell biology; pathology; Morfologi; cellbiologi; patologi; Molecular Medicine; molekylär medicin genetik och patologi ;

    Abstract : Gliomas are the most common primary tumors of the central nervous system believed to arise from glial cells. Invasive growth and inherent propensity for malignant progression make gliomas incurable despite extensive treatment. READ MORE

  6. 14. Development and evaluation of rehabilitation at home after stroke in south-west Stockholm

    Author : Lotta Widén Holmqvist; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : In Sweden (population 8.8 million) the great majority of patients with acute stroke are admitted to hospital. Each year 10 000-12 000 patients develop persistent disability. READ MORE

  7. 15. Alterations in the PI3K/AKT Signaling Pathway and Response to Adjuvant Treatment in Breast Cancer

    Author : Gizeh Pérez-Tenorio; Olle Stål; Anne Lykkesfeldt; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; Onkologi;

    Abstract : (PI3K)/AKT signaling pathway could be a cause of therapeutic resistance in breast cancer. The PI3K/AKT pathway controls cell proliferation, cell growth and survival, and its members include oncogenes and tumor suppressor genes. Alterations in this pathway are frequent in cancer. READ MORE