Search for dissertations about: "anti-tumor immunity"
Showing result 1 - 5 of 40 swedish dissertations containing the words anti-tumor immunity.
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1. Nitric Oxide Regulation during Anti-tumor Immunotherapy
Abstract : During tumor progression a strong immunosuppression is developed and is believed to be the major reason why immunotherapy fails. This suppression is induced in response to factors produced from tumor cells, but can also be induced after immunotherapy. READ MORE
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2. Immune modulation in serous epithelial ovarian cancer : focus on the role of tumor-derived exosomes
Abstract : Serous epithelial ovarian cancer (EOC) is a potent suppressor of the immune defense. Here, we studied interactions between EOC and the immune system that lead to escape from tumor immune surveillance. READ MORE
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3. Enhancing T cell mediated immunity in DNA vaccination
Abstract : For centuries infectious diseases have been one of the main causes of death in the world. With the invention of vaccine technology 200 years ago, we have been able to impede and even eradicate several dangerous pathogens. READ MORE
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4. Immunity and immunosuppression in the tumor-host interaction
Abstract : With the advent of new methods in molecular biology and in peptide isolation, a number of tumor-associated antigens and their epitopes have been identified and characterized. However, tumors often grow progressively evolving different mechanisms of immune escape, resulting in resistance to MHC class I-restricted tumor-specific T cells. READ MORE
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5. Adaptive immunity in urothelial cancer : molecular and clinical aspects
Abstract : In the battle between the immune system and cancer, tolerance mechanisms otherwise protective against autoimmunity, are exploited to halt the anti-tumor immune response. In this model, tumors turn distinct parts of the immune system against each other; suppressive cells such as regulatory T cells (Tregs) are hijacked to obstruct effector lymphocytes in their attempt to eradicate the tumor. READ MORE