Search for dissertations about: "NK-cells"

Showing result 51 - 55 of 258 swedish dissertations containing the word NK-cells.

  2. 51. Receptor localization and dynamics of murine natural killer cells at single cell level : using advanced fluorescence microscopy

    Author : Sunitha Bagawath Singh; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Natural Killer (NK) cells are immune cells and important for the defense against virally infected and malignant cells. NK cells are regulated by germline encoded activating and inhibitory receptors. Activating receptors specifically recognize ligands which are either encoded by infectious agents, or induced upon infection or cellular stress. READ MORE

  4. 52. Function of natural killer cells in Helicobacter pylori infection and gastric cancer

    Author : Åsa Lindgren; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Natural killer cells; Helicobacter pylori; gastric cancer; IFN-γ; TLR;

    Abstract : Helicobacter pylori infection is one of the most wide-spread infections in the world and causes a chronic inflammation in the gastrointestinal mucosa characterised by increased production of IFN-γ and is associated with an increased risk of developing gastric cancer. The mechanisms behind the development of gastric cancer in H. READ MORE

  5. 53. From natural to eximious : harnessing the power of natural killer cells against solid tumors

    Author : Ziqing Chen; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Cancer heterogeneity, which enables clonal survival and treatment resistance, is shaped by active immune responses. Unchallenged results from clinical trials show the power of stimulating our immune system to attack tumor cells. Engineered T cells and checkpoint blockade are at the forefront of current immunotherapy strategies. READ MORE

  6. 54. Single cell studies of natural killer cell immune surveillance

    Author : Elin Forslund; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Our immune system protects us from microbes such as viruses, bacteria and parasitic worms. The immune system also plays a key role in fighting cancer and in carrying out a function termed ‘immune surveillance’, natural killer (NK) cells patrol tissues and participate in the elimination of transformed cells and established tumors. READ MORE

  7. 55. NK Cell Cytotoxicity at the Single Cell Level

    Author : Ludwig Brandt; Björn Önfelt; Fredrik Bergh Thorén; KTH; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Biological Physics; Biologisk fysik;

    Abstract : Natural killer (NK) cells are innate immune cells with the ability to recognize and eliminate virally infected cells and cancer cells without prior sensitization. There is a functional heterogeneity between individual NK cells, where some NK cells are more efficient at killing cancer cells than others. READ MORE