Search for dissertations about: "chiral phosphine"

Showing result 1 - 5 of 15 swedish dissertations containing the words chiral phosphine.

2. 1. Synthesis and Applications of P-chirogenic Phosphine Boranes

   Author : Magnus Johansson; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; cytisine; gold I catalysis lipase; P-chirogenic; desymmetrization; phosphine; enantioselective cyclopropanation. enantioselective deprotonation; chirality; asymmetric synthesis; borane;

   Abstract : AbstractThis thesis reports the independent synthesis of both enantiomers of P-chirogenic phosphine ligands and the building blocks thereof, which are suitable for parallel synthesis efforts and for the generation of more diverse libraries of P-chirogenic compound. The use of P-chirogenic phosphine boranes in transition metal-catalyzed reactions, such as palladium-catalyzed allylic alkylation and amination, is also described. READ MORE

4. 2. Synthesis and Applications of P-Chirogenic and Axially Chiral P,N-Phosphines as Ligands and Organocatalyst

   Author : Kristian Andersson; Chalmers tekniska högskola; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; phosphoramidite; organocatalysis; aminophosphine; Nicholas reaction; asymmetric synthesis; phosphine; asymmetric hydrogenation; modular synthesis; P-chirogenic;

   Abstract : This thesis deals with the enantioselective synthesis of chiral mixed phosphorous/nitrogen compounds and some of their applications in asymmetric synthesis. For the most part, the compounds are P-chirogenic, with the chirality centered on the phosphorous atom. The last part of the thesis deals with axially chiral phosphoramidites. READ MORE

5. 3. Silaborations of Unsaturated Compounds

   Author : Martin Gerdin; Christina Moberg; Kálmán Szabó; KTH; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allylboration; bismetallation; boron; carbocyclization; catalysis; 1; 3-diene; enantioselective; 1; 6-enyne; interelement; N-heterocyclic carbene; nickel; palladium; phosphine; phosphoramidite; platinum; reaction mechanism; silaboration; silicon; silylborane; stereoselective; Chemistry; Kemi;

   Abstract : This thesis deals with the development of transition metal-catalyzed silaborations of 1,3-dienes and 1,6-enynes. The first part of the thesis describes the development of the enantioselective 1,4-silaboration of 1,3-cyclohexadiene. A number of chiral metal-ligand complexes were evaluated. READ MORE

6. 4. Synthesis of Novel Chiral Bicyclic Ligands and their Application in Iridium-Catalyzed Reactions

   Author : Anna Trifonova; Pher G. Andersson; Guy Lloyd-Jones; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; asymmetric catalysis; Diels-Alder reaction; transfer hydrogenation; hydrogenation; amino-oxazoline; phosphine-oxazoline; imine; olefin; Organisk kemi; Organic chemistry; Organisk kemi;

   Abstract : The synthesis of 2-aza-norborane derivatives is presented. The use of these compounds in preparation of Ir catalysts for asymmetric hydrogenations is described. The evaluation and optimization of the catalysts as well as the mechanistic aspects of the catalytic process are discussed. READ MORE

7. 5. Homogeneous and Heterogeneous Cluster-Based Catalysts for Asymmetric Reactions

   Author : Ahmed Fawzy; Kemisk fysik; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; Asymmetric synthesis; hydrogenation; ruthenium; osmium; rhenium; phosphine ligands; chirality.;

   Abstract : Synthesis and characterization of new transition metal carbonyl clusters has been undertaken, and evaluation of the new clusters to act as catalysts/catalysts precursor in asymmetric reactions has been carried out. The catalytic hydrogenation of tiglic acid under relatively mild conditions, using diastereomeric clusters of the general formula [(µ-H)2Ru3(µ3-S)(CO)7(µ-1,2-L)] (L= chiral diphosphine of the ferrocene-based Walphos and Josiphos families) as catalysts, reveal different catalytic behavior in terms of conversion and enantioselectivity. READ MORE