Search for dissertations about: "early-life microbial exposure"

Found 4 swedish dissertations containing the words early-life microbial exposure.

  1. 1. Microbial and maternal influences on allergic sensitization during childhood: defining a role for monocytes

    University dissertation from Stockholm : The Wenner-Gren Institute, Stockholm University

    Author : Shanie Saghafian Hedengren; Eva Sverremark-Ekström; Susan Prescott; [2009]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Monocytes; allergic sensitization; maternal allergy; Toll-like receptor; p38-MAPK; IL-6; Epstein-Barr virus; early-life microbial exposure; NK cells; IFN-γ; MEDICINE Microbiology; immunology; infectious diseases Immunology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Immunologi; immunologi; Immunology;

    Abstract : Allergic diseases are influenced by genetics and the environment. Maternal allergy appears to confer a higher risk for allergic sensitization than paternal allergy, suggesting an in utero influence. READ MORE

  2. 2. The Gut Bacterial Flora - Focus on Early Life and Physiological Traits

    University dissertation from Stockholm : The Wenner-Gren Institute, Stockholm University

    Author : Caroline Linninge; [2011]
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; gut microbiota; atopic eczema; inflammation; bacterial diversity; Escherichia coli; Lactobacillus plantarum; molecular-genetic methods;

    Abstract : The gastrointestinal tract of the foetus is considered sterile but during vaginal birth the neonate comes into contact with bacteria from the maternal vaginal and intestinal microbiota. The main focus of this doctoral thesis was to elucidate the initial bacterial ecosystem in newborns and to relate microbial perturbations to physiological traits. READ MORE

  3. 3. Early-life gut microbiota and breast milk oligosaccharides in relation to childhood immune maturation and allergy

    University dissertation from Stockholm : Wenner-Gren Institute for Experimental Biology, Stockholm University

    Author : Ylva Margareta Sjögren; Eva Sverremark-Ekström; Outi Vaarala; [2009]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; allergy; infant; gut microbiota; human milk oligosaccharides; Bifidobacterium; Lactobacillus; Bacteroides fragilis; Clostridium difficile; family size; secretory IgA; toll like receptor; NATURAL SCIENCES Biology Cell and molecular biology Immunology; NATURVETENSKAP Biologi Cell- och molekylärbiologi Immunologi; immunologi; Immunology;

    Abstract : Atopic allergy is the most common chronic disease among children in the developed world. This high prevalence could be associated with low microbial exposure. The early gut microbiota appears to be important for immune maturation. READ MORE

  4. 4. Gut microbes and the developing brain

    University dissertation from Stockholm : Karolinska Institutet, Dept of Neuroscience

    Author : Tim Arentsen; Karolinska Institutet.; Karolinska Institutet.; [2017]
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Abstract : The discovery that commensal gut microbiota can influence host development and physiology beyond the gastrointestinal (GI) tract has triggered a paradigm shift in our conceptualization of the origin of human diseases. A growing body of preclinical research has demonstrated that gut microbiota exert a modulatory role on the development and function of brain circuits involved in motor control, emotion and cognition. READ MORE