Search for dissertations about: "in situ generation"

Showing result 1 - 5 of 105 swedish dissertations containing the words in situ generation.

  1. 1. In situ Sequencing : Methods for spatially-resolved transcriptome analysis

    Author : Marco Mignardi; Mats Nilsson; Xiaoliang Sunney Xie; Stockholms universitet; []
    Keywords : MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Padlock probes; rolling circle amplification; in situ sequencing; spatially-resolved transcriptomics; molecular diagnostics; biokemi; Biochemistry;

    Abstract : It is well known that cells in tissues display a large heterogeneity in gene expression due to differences in cell lineage origin and variation in the local environment at different sites in the tissue, a heterogeneity that is difficult to study by analyzing bulk RNA extracts from tissue. Recently, genome-wide transcriptome analysis technologies have enabled the analysis of this variation with single-cell resolution. READ MORE

  2. 2. On the deformation behavior and cracking of ductile iron; effect of microstructure

    Author : Keivan Amiri Kasvayee; Anders E.W. Jarfors; Jens Bergström; Högskolan i Jönköping; []
    Keywords : ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Spherical graphite iron; component casting; high silicon ductile iron; digital image correlation DIC ; in-situ tensile testing; in-situ cyclic testing; DIC pattern generation; pit etching; micro-scale deformation; micro-crack; finite element analysis FEA ; focused ion beam FIB milling; segjärn; komponentgjutning; högkisellegerat segjärn; digital image correlation DIC ; insitu dragprovning; in-situ cyklisk provning; DIC-mönstergenerering; grop-etsning; mikroskalig deformation; mikrosprickor; finite element analys FEA ; fokuserad jonstråle FIB avverkning;

    Abstract : This thesis focuses on the effect of microstructural variation on the mechanical properties and deformation behavior of ductile iron. To research and determine these effects, two grades of ductile iron, (i) GJS-500-7 and (ii) high silicon GJS-500-14, were cast in a geometry containing several plates with different section thicknesses in order to produce microstructural variation. READ MORE

  3. 3. Domain engineering in KTiOPO4

    Author : Carlota Canalias; Fredrik Laurell; Benoît Boulanger; KTH; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; quasi-phase matching; KTiOPO4; ferroelectric domains; atomic force microscopy; periodic electric field poling; polarization switching; second harmonic generation; Optical physics; Optisk fysik;

    Abstract : Ferroelectric crystals are commonly used in nonlinear optics for frequency conversion of laser radiation. The quasi-phase matching (QPM) approach uses a periodically modulated nonlinearity that can be achieved by periodically inverting domains in ferroelectric crystals and allows versatile and efficient frequency conversion in the whole transparency region of the material. READ MORE

  4. 4. Generation of induced neurons via direct conversion in vivo and in vitro

    Author : Olof Torper; Neurobiologi; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cellular reprogramming; cell replacement therapies; induced dopaminergic neurons; in vivo reprogramming; Lentiviral vectors; AAV vectors;

    Abstract : Cellular reprogramming is when one cell is changed into another. This involves structural modifications on the DNA of a cell resulting in a transcriptional change. This occurs naturally during development when early pluripotent cells gradually differentiate into more specialized cells that finally result in a complete organism. READ MORE

  5. 5. Thin metal films on weakly-interacting substrates : Nanoscale growth dynamics, stress generation, and morphology manipulation

    Author : Andreas Jamnig; Kostas Sarakinos; Gregory Abadias; Gregory Thompson; Linköpings universitet; []
    Keywords : NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Thin films; magnetron sputter-deposition; in situ and real-time characterization; early film growth stages; residual stress; manipulation of morphology; Couches minces; pulvérisation magnétron; caractérisation in situ en temps réel; premiers stades de croissance; contraintes résiduelles; manipulation de morphologie;

    Abstract : Vapor-based growth of thin metal films with controlled morphology on weakly-interacting substrates (WIS), including oxides and van der Waals materials, is essential for the fabrication of multifunctional metal contacts in a wide array of optoelectronic devices. Achieving this entails a great challenge, since weak film/substrate interactions yield a pronounced and uncontrolled 3D morphology. READ MORE