Search for dissertations about: "circle-to-circle amplification"
Found 5 swedish dissertations containing the words circle-to-circle amplification.
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1. Detection and Sequencing of Amplified Single Molecules
Abstract : Improved analytical methods provide new opportunities for both biological research and medical applications. This thesis describes several novel molecular techniques for nucleic acid and protein analysis based on detection or sequencing of amplified single molecules (ASMs). READ MORE
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2. Visual and magnetic detection of antimicrobial resistance genes using nanoparticles and isothermal amplification
Abstract : Antibiotic resistance is becoming an increasing concern, necessitating new ways to diagnose and treat it rapidly and accurately. One proposed solution is the use of nucleic acid amplification tests, capable of detecting resistance in just a few hours, as opposed to the several days that traditional testing methods may require. READ MORE
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3. Single Molecule Detection : Microfluidic Automation and Digital Quantification
Abstract : Much of recent progress in medical research and diagnostics has been enabled through the advances in molecular analysis technologies, which now permit the detection and analysis of single molecules with high sensitivity and specificity. Assay sensitivity is fundamentally limited by the efficiency of the detection method used for read-out. READ MORE
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4. Selector Technology : For Multiplex DNA Analysis
Abstract : A majority of methods for identifying sequences in the human genome involve target sequence amplification through PCR. This work presents novel methods for amplifying circularized DNA and presents solutions for some major limitations of PCR. READ MORE
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5. Cell and organoid models to develop new antivirals and diagnostic methods for emerging viruses
Abstract : The ongoing global pandemic of severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) is only the latest reminder of the urgent need for new antiviral strategies and diagnostic tools to improve preparedness for emergence of new pathogenic RNA-viruses. A key obstacle for the development of antivirals and diagnostic tools has been the lack of good models to study RNA viruses. READ MORE