Search for dissertations about: "digestive diseases"

Showing result 1 - 5 of 14 swedish dissertations containing the words digestive diseases.

  1. 1. Macrophages in Crohn's Disease: lnnate immune cellular and molecular mechanisms driving intestinal inflammation and fibrosis

    Author : Frida Gorreja; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; macrophages; inflammatory macrophages; tissue-resident macrophages; efferocytosis; innate immunity; myeloid cells; fibroblasts; fibrosis; inflammasomes; Crohn´s disease; inflammatory bowel diseases; digestive diseases; mucosa immunology; intestinal immunity; intestinal inflammation; serum systemic inflammation; microbiota; metabolites;

    Abstract : Macrophages and their interactions with the lamina propria and luminal microenvi-ronment are crucial in the pathogenesis of Crohn´s disease (CD), a chronic inflamma-tory disease with a strong inflammatory innate immune involvement. Therefore, in-terpreting macrophage activity in the intestinal microenvironment may identify treatment targets beneficial for at least a subgroup of patients. READ MORE

  2. 2. Musculoskeletal Disorders among Farmers and Referents, with Special Reference to Occurence, Health Care Utilization and Etiological Factors : A Population-based Study

    Author : Sara Holmberg; Kurt Svärdsudd; Anders Thelin; Anders Håkansson; Uppsala universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; farmers; agriculture; rural; musculoskeletal disorders; sick leave; low back pain; hip problems; physical workload; psychosocial factors; lifestyle; comorbidity; work-related fever attacks; epidemiology; etiology; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Abstract : Objectives. To study the prevalence of musculoskeletal symptoms among farmers as compared to rural referents and to evaluate the effects of physical work exposures, psychosocial factors, lifestyle and comorbidity.Material and methods. A cross-sectional population-based survey of 1013 farmers and 769 matched referents was performed. READ MORE

  3. 3. Impact of the gut microflora on the digestive system in the suckling rat

    Author : Frida Fåk; Biologiska institutionen; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; probiotics; prebiotics; antibiotics; lactobacilli; bacteria; intestinal permeability; Small intestine; maturation; weaning; suckling;

    Abstract : The postnatal development of the gastrointestinal (GI) system in mammals is genetically programmed, but is, to an unknown extent, regulated by external factors such as the diet and the gut microflora. These factors can influence the growth of the GI tract, the age-related pattern of appearance of digestive enzymes and the decreased intestinal macromolecular permeability at gut closure, normally timed with weaning in young rodents. READ MORE

  4. 4. Mortality and cancer incidence following cerebral angiography with thorotrast

    Author : Ullakarin Nyberg; Karolinska Institutet; Karolinska Institutet; []
    Keywords : ;

    Abstract : Epidemiological studies are important tools in assessing radiation-related health effects in humans. The most common form of radiation exposure is low-dose alpha-radiation such as that from radon. However, the long-term health effects of low-dose radiation are incompletely known. READ MORE

  5. 5. Symptom burden among people with chronic disease

    Author : Jeanette Eckerblad; Tiny Jaarsma; Ingrid Hellström; Kersti Theander; Anna-Karin Edberg; Linköpings universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Symptom experience; Symptom burden; Chronic disease; Community-dwelling;

    Abstract : Introduction: Chronic diseases tend to increase with old age. Older people with chronic disease are commonly suffering from conditions which produce a multiplicity of symptoms and a decreased health-related quality of life. READ MORE