Search for dissertations about: "gas phase protein structure"
Showing result 1 - 5 of 21 swedish dissertations containing the words gas phase protein structure.
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1. Gas-Phase Protein Structure Under the Computational Microscope : Hydration, Titration, and Temperature
Abstract : Although the native environment of the vast majority of proteins is a complex aqueous solution, like the interior of a cell, many analysis methods for assessing chemical and physical properties of biomolecules require the sample to be aerosolized; that is, transferred to the gas-phase. An important example is electrospray-ionization mass spectrometry, which can provide a wide range of information about e. READ MORE
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2. Theoretical and Biochemical : Advancing Protein Structure Investigations with Complementing Computations
Abstract : Life as we know it today would not exist without proteins. The functions of proteins for us and other organisms are linked to their three-dimensional structures. As such, protein structure investigations are a crucial contribution for understanding proteins and the molecular basis of life. READ MORE
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3. Exploring the Molecular Dynamics of Proteins and Viruses
Abstract : Knowledge about structure and dynamics of the important biological macromolecules — proteins, nucleic acids, lipids and sugars — helps to understand their function. Atomic-resolution structures of macromolecules are routinely captured with X-ray crystallography and other techniques. READ MORE
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4. Mass spectrometry in protein structure analysis
Abstract : Mass spectrometry is an important analytical tool in biological and biochemical research. The speed, accuracy and sensitivity is unmatched by conventional analytical techniques. READ MORE
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5. Protein Folding and DNA Origami
Abstract : In this thesis, the folding process of the de novo designed polypeptide chignolin was elucidated through atomic-scale Molecular Dynamics (MD) computer simulations. In a series of long timescale and replica exchange MD simulations, chignolin’s folding and unfolding was observed numerous times and the native state was identified from the computed Gibbs free-energy landscape. READ MORE