Search for dissertations about: "Bioinformatics"

Showing result 1 - 5 of 471 swedish dissertations containing the word Bioinformatics.

  1. 1. eScience Approaches to Model Selection and Assessment Applications in Bioinformatics

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Martin Eklund; Jarl Wikberg; Ron Wehrens; [2009]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; bioinformatics; high-throughout biology; eScience; model selection; model assessment; TECHNOLOGY Bioengineering Bioinformatics; TEKNIKVETENSKAP Bioteknik Bioinformatik;

    Abstract : High-throughput experimental methods, such as DNA and protein microarrays, have become ubiquitous and indispensable tools in biology and biomedicine, and the number of high-throughput technologies is constantly increasing. They provide the power to measure thousands of properties of a biological system in a single experiment and have the potential to revolutionize our understanding of biology and medicine. READ MORE

  2. 2. Fusing Domain Knowledge with Data Applications in Bioinformatics

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Claes Andersson; Jan Komorowski; Mats Gustafsson; Yves Moreau; [2008]
    Keywords : Bioinformatics; cell cycle; cancer chemotherapy; predictive tests; performance estimation; bioinformatics; Bioinformatik;

    Abstract : Massively parallel measurement techniques can be used for generating hypotheses about the molecular underpinnings of a biological systems. This thesis investigates how domain knowledge can be fused to data from different sources in order to generate more sophisticated hypotheses and improved analyses. READ MORE

  3. 3. Analysis of RNA and DNA sequencing data Improved bioinformatics applications

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Benjamín Sigurgeirsson; Joakim Lundeberg; Simon Anders; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; RNA sequencing; exome sequencing; bioinformatics; gene expression; differential expression; variant calling; Biotechnology; Bioteknologi;

    Abstract : Massively parallel sequencing has rapidly revolutionized DNA and RNA research. Sample preparations are steadfastly advancing, sequencing costs have plummeted and throughput is ever growing. This progress has resulted in exponential growth in data generation with a corresponding demand for bioinformatic solutions. READ MORE

  4. 4. Improved Neuropeptide Identification Bioinformatics and Mass Spectrometry

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Maria Fälth Savitski; Per Andrén; David Fenyö; Per Svenningsson; Ronald Beavis; [2008]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; bioinformatics; neuropepides; database; peptide identification; peptide fragmentation; mass spectrometry; tandem mass spectromerty; NATURAL SCIENCES Chemistry Theoretical chemistry Bioinformatics; NATURVETENSKAP Kemi Teoretisk kemi Bioinformatik;

    Abstract : Bioinformatic methods were developed for improved identification of endogenous peptides using mass spectrometry. As a framework for these methods, a database for endogenous peptides, SwePep, was created. It was designed for storing information about endogenous peptides including tandem mass spectra. READ MORE

  5. 5. A Study in RNA Bioinformatics Identification, Prediction and Analysis

    University dissertation from Uppsala : Acta Universitatis Upsaliensis

    Author : Eva Freyhult; David Ardell; Robert Giegerich; [2007]
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; RNA; bioinformatics; secondary structure; structure prediction; dynamic programming; energy landscape; homology search; sequence logo; tRNA; NATURAL SCIENCES Chemistry Theoretical chemistry Bioinformatics; NATURVETENSKAP Kemi Teoretisk kemi Bioinformatik;

    Abstract : Research in the last few decades has revealed the great capacity of the RNA molecule. RNA, which previously was assumed to play a main role only as an intermediate in the translation of genes to proteins, is today known to play many important roles in the cell in addition to that as a messenger RNA and transfer RNA, including the ability to catalyze reactions and gene regulations at various levels. READ MORE