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Showing result 1 - 5 of 143 swedish dissertations matching the above criteria.

2. 1. Uncovering biomarkers and molecular heterogeneity of complex diseases : Utilizing the power of Data Science

   Author : Sara Younes; Linda Holmfeldt; Jan Komoroski; Aedin Culhane; Uppsala universitet; []
   Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Complex Disease; Cancer; Autoimmune diseases; Acute Myeloid Leukemia; Systemic Lupus Erythematosus; Bioinformatics; Machine Learning; Data Science; Statistical Analysis; Bioinformatics; Bioinformatik; Computer Science; Datavetenskap;

   Abstract : Uncovering causal drivers of complex diseases is yet a difficult challenge. Unlike single-gene disorders complex diseases are heterogeneous and are caused by a combination of genetic, environmental, and lifestyle factors which complicates the identification of patient subgroups and the disease causal drivers. READ MORE

4. 2. Berries in Prevention of Metabolic Disease – focus on obesity, diabetes and gut microbiota

   Author : Lovisa Heyman; Molekylär nutrition; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; obesity; type 2 diabetes; berries; low-grade inflammation; gut microbiota; hepatic steatosis; gene expression; DNA methylation; lingonberry; blackcurrant; bilberry; açai;

   Abstract : The increasing prevalence of obesity is a worldwide health problem closely linked to diet and lifestyle factors. Obesity is associated with increased risk of several metabolic disorders including insulin resistance, nonalcoholic fatty liver disease and type 2 diabetes. READ MORE

5. 3. Exploring vitamin D and steroid hormone receptors – from healthy elderly to prostate cancer cells

   Author : Maria Araceli Diaz Cruz; Maria Faresjö; Dennis Larsson Dennis Larsson; Johan Staaf; Jönköping University; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; vitamin D; steroid hormone receptors; lifestyle; methylation; SNPs; healthy elderly; prostate cancer cells; crosstalk; PDIA3;

   Abstract : The genetic background together with environmental factors and lifestyle are key contributors to the health of an individual. Genetic background is inherited and irreversible unless mutations occur. However, lifestyle habits (i.e. READ MORE

6. 4. Musculoskeletal Disorders among Farmers and Referents, with Special Reference to Occurence, Health Care Utilization and Etiological Factors : A Population-based Study

   Author : Sara Holmberg; Kurt Svärdsudd; Anders Thelin; Anders Håkansson; Uppsala universitet; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; farmers; agriculture; rural; musculoskeletal disorders; sick leave; low back pain; hip problems; physical workload; psychosocial factors; lifestyle; comorbidity; work-related fever attacks; epidemiology; etiology; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

   Abstract : Objectives. To study the prevalence of musculoskeletal symptoms among farmers as compared to rural referents and to evaluate the effects of physical work exposures, psychosocial factors, lifestyle and comorbidity.Material and methods. A cross-sectional population-based survey of 1013 farmers and 769 matched referents was performed. READ MORE

7. 5. Evolving geriatric anthropometrics- an interplay with lifestyle changes, birth cohort effects, and survival implications. : Results from the general population study, “Good Aging in Skåne,” Sweden

   Author : Nivetha Natarajan Gavriilidou; Geriatrik; []
   Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anthropometrics; BMI misclassification; measurement; error correction; prediction equation; surrogate; survival; lifestyle; birth cohort; Swedish elderly; assessment;

   Abstract : There is a rising proportion of aging population worldwide. The high vulnerability of older adults to morbidity and mortality introduces an enormous health and economic burden to themselves and the society. The established leading cause of death among older adults is due to chronic and vascular diseases. READ MORE