Search for dissertations about: "small molecule inhibitor"
Showing result 1 - 5 of 89 swedish dissertations containing the words small molecule inhibitor.
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1. Design, Synthesis and Characterization of Small Molecule Inhibitors and Small Molecule : Peptide Conjugates as Protein Actors
Abstract : This thesis describes different aspects of protein interactions. Initially the function of peptides and their conjugates with small molecule inhibitors on the surface of Human Carbonic Anhydrase isoenzyme II (HCAII) is evaluated. READ MORE
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2. Modeling normal and malignant hematopoiesis in vitro. To screen for extrinsic regulators and differentiation therapy
Abstract : The incredible thing with blood stem cells, also known as hematopoietic stem cells (HSC), is that they can restore normal hematopoiesis in patients that need a new blood system. Since a prerequisite for successful transplantation is immune compatibility, it requires large donor registries to find a suitable match for a recipient. READ MORE
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3. The discovery of antiviral compounds targeting adenovirus and herpes simplex virus : assessment of synthetic compounds and natural products
Abstract : There is a need for new antiviral drugs. Especially for the treatment of adenovirus infections, since no approved anti-adenoviral drugs are available. Adenovirus infections in healthy persons are most often associated with respiratory disease, diarrhea and infections of the eye. These infections can be severe, but are most often self-limiting. READ MORE
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4. Targeting Nutrient Transporters in Acute Myeloid Leukemia
Abstract : .... READ MORE
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5. Shedding light on the STAT3 small molecule inhibitor field
Abstract : STAT3 is one of the seven family members of the STAT transcription factor family. STAT3 has become a very attractive target for cancer therapy and other diseases. It has a prominent role in cancer development as well as progression. However, there are still no STAT3 inhibitors applied in the clinic. READ MORE