Search for dissertations about: "genetic polymorphism response"
Showing result 1 - 5 of 97 swedish dissertations containing the words genetic polymorphism response.
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1. Genetic variation and prostate cancer : population-based association studies in Sweden
Abstract : Prostate cancer constitutes the most common malignancy and the most common cause of cancer‐related death in Swedish men. A large body of evidence suggests that inherited genetic variants contribute to both development and progression of prostate cancer. READ MORE
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2. Recurrent Aphthous Stomatitis - A study, with emphasis on host genetics, oral microbiota composition, and immunoregulatory networks
Abstract : Recurrent aphthous stomatitis (RAS) is one of the most common oral mucosal lesions. The aetiology is unknown and currently there is no consensus regarding suitable treatment regimens. READ MORE
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3. Search for Type 2 Diabetes Susceptibility Genes Using Multiple Approaches
Abstract : Type 2 diabetes mellitus is a multifactorial disorder characterized by chronic hyperglycemia resulting from pancreatic dysfunction and insulin resistance. It is a common disorder with a complex pattern of inheritance, likely to reflect the influence of multiple genetic and environmental factors on the diabetes risk. READ MORE
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4. Osteogenesis Imperfecta : Genetic and Therapeutic Studies
Abstract : Osteogenesis imperfecta (OI) is a heterogeneous disease of connective tissue, the cardinal symptom being fractures and severity ranging from mild to lethal. Dominant mutations in collagen I, encoded by COL1A1 and COL1A2, cause >90% of cases. READ MORE
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5. Genetic polymorphism and regulation of cytochrome P450 2E1
Abstract : Cytochrome P450 2E1 (CYP2E1) participates in the metabolism of several xenobiotics. A physiological role of CYP2E1 is its ability to convert acetone into gluconeogenetic precursors. Due to a pronounced oxidase activity CYP2E1 can generate substantial amount of oxygen free radicals and may contribute to oxidative stress. READ MORE