Search for dissertations about: "amino acid secretion"

Showing result 1 - 5 of 49 swedish dissertations containing the words amino acid secretion.

  1. 1. Cellular transport and secretion of the cyanobacterial neurotoxin BMAA into milk and egg : Implications for developmental neurotoxicity

    Author : Marie Andersson; Ingvar Brandt; Cynthia de Wit; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; BMAA; beta-N-methylamino-L-alanine; milk; secretion; amino acid transporter; autoradiography; metabolism; Biologi med inriktning mot ekotoxikologi; Biology with specialization in Environmental Toxicology;

    Abstract : The cyanobacterial amino acid β-N-methylamino-L-alanine (BMAA) is a neurotoxin implicated in the etiology of neurodegenerative diseases. Cyanobacteria are cosmopolitan organisms present in various environments. READ MORE

  2. 2. Analysis and engineering of central metabolism in Clostridium thermocellum

    Author : Teun Kuil; Antonius J. A. van Maris; Ruud Weusthuis; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Clostridium thermocellum; biofuels; ethanol; atypical glycolysis; pyrophosphate; phosphofructokinase; thermodynamic driving force; redox cofactor balancing; amino acid secretion; chaotropicity; hexose utilization; laboratory evolution; metabolic engineering; Biotechnology; Bioteknologi;

    Abstract : To mitigate climate change, greenhouse gas emissions must be reduced to net-zero in 2050 requiring a drastic transition in today´s energy sector. To achieve this goal, the use of biofuels produced from lignocellulosic feedstocks, including agricultural and forestry residues, is expected to play an important role. READ MORE

  3. 3. Macroscopic models of Chinese hamster ovary cell cultures

    Author : Erika Hagrot; Véronique Chotteau; Anders Forsgren; Nathan E. Lewis; KTH; []
    Keywords : TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Chinese hamster ovary; Amino acid; Metabolic network; Metabolic flux analysis; Kinetic modeling; Elementary flux mode; Optimization; Column generation; Bioteknologi; Biotechnology;

    Abstract : Biopharmaceuticals treat a range of diseases, and is a growing sector within the pharmaceutical industry. A majority of these complex molecules are produced by genetically modified mammalian cells in large-scale cell cultures. READ MORE

  4. 4. Insulinogenic Effects of Milk- and Other Dietary Proteins, Mechanisms and metabolic implications

    Author : Mikael Nilsson; Avdelningen för livsmedel och läkemedel; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Näringslära; Nutrition; Type 2 diabetes; Isolated islets; Incretin hormones; Food proteins; Amino acids; Insulin index; Glycaemic index; Hyperinsulinaemia; Insulin; Blood glucose; Milk; Whey;

    Abstract : The metabolic syndrome (type 2 diabetes, obesity, hypertension, atherosclerotic cardiovascular disease, dyslipidaemia, and hyperinsulinaemia), is increasing in prevalence world-wide. The progression of this syndrome proceeds through a step-wise deterioration of metabolic events where deterioration of insulin sensitivity appears to have a key role in a ?vicious circle? of hyperinsulinaemia/hyperglycaemia and insulin resistance. READ MORE

  5. 5. Enterostatin in the Gastrointestinal Tract - Production and Possible Mechanism of Action

    Author : Maria Sörhede Winzell; Lund Medicin; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; insulin secretion; neuropeptide; lipolysis; appetite; Colipase; fat intake; Fysiologi;

    Abstract : The presence of procolipase and enterostatin in the rat gastrointestinal tract has been investigated. Procolipase was identified, using in situ hybridization and immunohistochemistry, in exocrine cells of the pancreas as well as in chief cells of the fundus region of the stomach. READ MORE