Search for dissertations about: "RT PCR"

Showing result 6 - 10 of 315 swedish dissertations containing the words RT PCR.

  2. 6. The Origin of the Genus Flavivirus and the Ecology of Tick-Borne Pathogens

    Author : John H.-O. Pettersson; Thomas Jaenson; Sven Bergström; Kenneth Nilsson; Mikael Thollesson; Per-Eric Lindgren; Uppsala universitet; []
    Keywords : NATURVETENSKAP; NATURAL SCIENCES; Flavivirus; Virus dating; Molecular dating; Biogeography; Ixodes ricinus; Minimum infection rate; TBE; Tick-borne encephalitis virus; Rickettsia helvetica; Anaplasma phagocytophilum; Infection prevalence; RT-PCR; Biology with specialization in Systematics; Biologi med inriktning mot systematik;

    Abstract : The present thesis examines questions related to the temporal origin of the Flavivirus genus and the ecology of tick-borne pathogens. In the first study, we date the origin and divergence time of the Flavivirus genus. It has been argued that the first flaviviruses originated after the last glacial maximum. READ MORE

  4. 7. Hypoxia inducible factor-1α in renal cell carcinoma

    Author : Anders Lidgren; Börje Ljungberg; Torgny Rasmuson; Kjell Grankvist; Anders Bergh; Per-Uno Malmström; Umeå universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; renal cell carcinoma; hypoxia; RT-PCR; angiogenesis; western blot; tissue microarray; protein; mRNA; HIF-1 alpha; GLUT-1; survival; Urology and andrology; Urologi och andrologi;

    Abstract : Hypoxia Inducible Factor-1α in Renal Cell Carcinoma Departments of Surgical and Perioperative Sciences, Urology and Andrology; Radiation Sciences, Oncology; Medical Biosciences, Pathology; and Medical Biosciences, Clinical Chemistry, Umeå University, Umeå, Sweden Background: Renal cell carcinoma (RCC) accounts for approximately 2-3% of all human cancers. A distinguished feature of RCC is vascularisation and among the three dominating RCC types conventional RCC (cRCC) generally is more vascularised than papillary RCC (pRCC) and chromophobe RCC (chRCC). READ MORE

  5. 8. Identification of abnormally expressed genes in skeletal muscle contributing to insulin resistance and type 2 diabetes

    Author : Xudong Huang; Malmö Institutionen för kliniska vetenskaper; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrinology; secreting systems; diabetology; Endokrinologi; gene expression; high-fat intake; RT-PCR; mitochondrial genes; cathepsin L; Shc; IRS-2; IRS-1; GS; cDNA differential display; Insulin resistance; type 2 diabetes; sekretion; diabetologi;

    Abstract : The metabolic defects of insulin resistance and type 2 diabetes can result from changes in gene expression and protein functions due to genetic and environmental influences. The aim of this study was to identify abnormally expressed genes associated with insulin resistance or type 2 diabetes, and further to test whether possible defects are inherited or acquired. READ MORE

  6. 9. Matrix metalloproteinases in natural killer cells. Expression of MMPs, IL-2 activation and killer cell interactions with Matrigel® and model tumours

    Author : Per Albertsson; Göteborgs universitet; []
    Keywords : MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Protease; matrix metalloproteinase; killer cell; IL-2; Matrigel; B16 melanoma; tumour infiltration; invasion assay; zymography; Western blot; RT-PCR; light microscopy; fluorescence; electron microscopy;

    Abstract : Introduction: IL-2 activated natural killer (A-NK) cells can recognize malignant cells and exert tumouricidal activities by multiple mechanisms that require close contact with the target cells. Upon adoptive transfer, some A-NK cells accumulate in tumours by migrating from the vascular bed to a position inside the malignant tissue, forming close contacts with target cells. READ MORE

  7. 10. Epidermal keratinocytes studied by X-ray microanalysis, with special reference to contact dermatitis : In vivo and in vitro studies of functional changes in human cells

    Author : Anders Grängsjö; Uppsala universitet; []
    Keywords : Medical sciences; X-ray microanalysis; elements; epidermis; keratinocytes; proliferation; cell membrane damage; Ki67; irritants; intracellular elemental content; keratinocyte culture; HaCaT; NHEK; RT-PCR; immunohistochemistry; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; anatomi; Human Anatomy;

    Abstract : By determining the intracellular elemental content, information can be obtained on the physiological status of cells. The cellular content of sodium, magnesium, phosphorus, sulfur, chloride, potassium and calcium can be indicative for proliferation, cell membrane damage or cell death. READ MORE